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| 購買進(jìn)口儀器、試劑和耗材——就在始于2001年的畢特博生物 www.effectnews.cn |
德國耶拿大學(xué)科研人員最新公布的一項(xiàng)研究結(jié)果表明，攝入微量鋰元素有助于一種線蟲延年益壽。 耶拿大學(xué)的研究者和日本同行在新一期《歐洲營養(yǎng)學(xué)期刊》（European Journal of Nutrition）上報(bào)告說，他們聯(lián)合對日本大分縣18個(gè)城鎮(zhèn)自來水的鋰含量與當(dāng)?shù)氐乃劳雎首髁讼嚓P(guān)性調(diào)查，結(jié)果發(fā)現(xiàn)在自來水鋰含量較高的城鎮(zhèn)，其人口死亡率明顯較低。 為了驗(yàn)證這種相關(guān)性，研究人員讓秀麗隱桿線蟲攝入微量鋰元素，其含量水平與日本大分縣低死亡率城鎮(zhèn)的自來水鋰含量相當(dāng)，結(jié)果發(fā)現(xiàn)攝入鋰元素的那些線蟲平均壽命也較高。 據(jù)耶拿大學(xué)人類營養(yǎng)學(xué)教授羅斯托介紹，鋰是一種人們主要通過吃蔬菜和飲用自來水?dāng)z入的生命活動(dòng)必備元素。耶拿大學(xué)此前曾在實(shí)驗(yàn)中發(fā)現(xiàn)秀麗隱桿線蟲攝入大量鋰元素后壽命明顯延長，但當(dāng)時(shí)使用的鋰劑量是自來水中常見鋰含量的1000倍，對人體有毒，所以科研人員此次又通過實(shí)驗(yàn)研究了微量的鋰對秀麗隱桿線蟲壽命的影響。 耶拿大學(xué)的研究者還指出，此前有一些研究發(fā)現(xiàn)，通過自來水較多地?cái)z入鋰元素有助于改善情緒，降低自殺率。但是科研人員迄今尚未完全了解鋰對人體生理的作用機(jī)理，雖不排除將來人類通過營養(yǎng)補(bǔ)充劑攝入微量鋰元素的可能性，但為證實(shí)其科學(xué)性和安全性還需作進(jìn)一步研究。 推薦原文出處： European Journal of Nutrition DOI: 10.1007/s00394-011-0171-x Low-dose lithium uptake promotes longevity in humans and metazoans Kim Zarse, Takeshi Terao, Jing Tian, Noboru Iwata, Nobuyoshi Ishii and Michael Ristow Abstract Purpose Lithium is a nutritionally essential trace element predominantly contained in vegetables, plant-derived foods, and drinking water. Environmental lithium exposure and concurrent nutritional intake vary considerably in different regions. We here have analyzed the possibility that low-dose lithium exposure may affect mortality in both metazoans and mammals. Methods Based on a large Japanese observational cohort, we have used weighted regression analysis to identify putative effects of tap water-derived lithium uptake on overall mortality. Independently, we have exposed Caenorhabditis elegans, a small roundworm commonly used for anti-aging studies, to comparable concentrations of lithium, and have quantified mortality during this intervention. Results In humans, we find here an inverse correlation between drinking water lithium concentrations and all-cause mortality in 18 neighboring Japanese municipalities with a total of 1,206,174 individuals (β = ?0.661, p = 0.003). Consistently, we find that exposure to a comparably low concentration of lithium chloride extends life span of C. elegans (p = 0.047). Conclusions Taken together, these findings indicate that long-term low-dose exposure to lithium may exert anti-aging capabilities and unambiguously decreases mortality in evolutionary distinct species. Keywords Trace elements – Lithium – Mortality – Longevity – Human – C. elegans |
購買進(jìn)口儀器、試劑和耗材——就在始于2001年的畢特博生物
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